Cardiovascular Diseases

QS scientists have worked on many projects in a wide range of indications in the cardiovascular area. The following is a list of indications and our experience level in each indication:
Extensive experience (over 10 projects): hypertension, DVT, dyslipidemia
Great experience (5-10 projects): acute coronary syndromes
Good experience (3-5 projects): stroke, CHF, AF, atherosclerosis
Some experience (< 3 projects): nephropathy

The following links show an example of the work on the design of an adaptive Phase II dose finding study for a novel factor Xa inhibitor:
QX Workshop
Paper on Factor Xa Inhibitor

The following article describes model based development of a new lipid-altering agent, Gemcabene, based on the analysis of publicly available summary-level data and proprietary patient-level data. Paper on lipid-altering agent